OR56B1

Across TCGA patient cohorts, OR56B1 mutation is significantly associated with the RNA expression of many other genes, with 2,475 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR56B1-associated genes across cancer lineages are DGKZ, TMEM138, and INCENP. Each is linked with OR56B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR56B1-to-partner and partner-to-OR56B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DGKZ grouped by OR56B1-low versus OR56B1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR56B1→partner) and Y-score (partner→OR56B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DGKZ →	+0.354	+3.470	.004	.002	3	2
UCEC	TMEM138 →	+0.246	+4.332	.007	<.001	3	2
UCEC	INCENP →	+0.651	+2.616	.002	.005	3	2
UCEC	CENPU →	+0.597	+2.617	.008	<.001	3	2
UCEC	CWC27 →	+0.533	+3.931	.001	<.001	3	2
UCEC	SUPV3L1 →	+0.402	+2.098	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,475 associations by consensus.

DGKZ by OR56B1 expression — UCEC

Explore this box plot interactively →