OR56B1

Across TCGA patient cohorts, OR56B1 mutation is significantly associated with the total protein of many other genes, with 44 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR56B1-associated genes across cancer lineages are INPP4B, mTOR_pS2448, and 4E-BP1. Each is linked with OR56B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR56B1-to-partner and partner-to-OR56B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INPP4B grouped by OR56B1-low versus OR56B1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR56B1→partner) and Y-score (partner→OR56B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INPP4B →	-0.401	-2.700	.003	.006	3	2
UCEC	mTOR_pS2448 →	-0.132	-2.302	.037	.034	3	2
SKCM	4E-BP1 →	+0.387	+3.321	.001	.009	3	2
UCEC	14-3-3_beta →	-0.098	-3.143	.021	.018	3	1
UCEC	eEF2 →	+0.452	+2.584	.002	.010	3	1
UCEC	EGFR_pY1068 →	-0.360	-2.906	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

INPP4B by OR56B1 expression — UCEC

Explore this box plot interactively →