Across TCGA pan-cancer cohorts, OR56A3 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated OR56A3 data layer compared with 14 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher OR56A3 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR56A3 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

HNSC, UCEC, and LUAD are the cancer types where OR56A3 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.247	0.663	.009	33	view →
UCEC	DFS	Median	All	1.000	0.628	.015	10	view →
LUAD	OS	Median	III,IV	0.083	0.680	<.001	8	view →
COAD	DFS	Median	II,III,IV	0.149	0.495	.014	7	view →
ACC	DFS	Median	All	0.089	0.666	.017	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: OR56A3 tumor-vs-normal RNA expression · all OR56A3 data types