OR56A1

Across TCGA patient cohorts, OR56A1 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR56A1-associated genes across cancer lineages are FoxM1, PDK1_pS241, and Acetyl-a-Tubulin-Lys40. Each is linked with OR56A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR56A1-to-partner and partner-to-OR56A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FoxM1 grouped by OR56A1-low versus OR56A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR56A1→partner) and Y-score (partner→OR56A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.251	+3.807	.031	<.001	3	2
LUSC	PDK1_pS241 →	+0.220	+2.816	.005	.036	2	2
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.743	+2.000	.001	.032	3	1
UCEC	MEK1 →	+0.477	+2.700	.003	.006	3	1
UCEC	Notch1 →	+0.189	+3.013	.002	.018	3	1
UCEC	PCNA →	+0.224	+2.000	.021	.032	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

FoxM1 by OR56A1 expression — UCEC

Explore this box plot interactively →