OR56A1

Across TCGA cell cohorts, OR56A1 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR56A1-associated genes across cancer lineages are CUX2, NEUROD4, and ASB15. Each is linked with OR56A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR56A1-to-partner and partner-to-OR56A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CUX2 grouped by OR56A1-low versus OR56A1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR56A1→partner) and Y-score (partner→OR56A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CUX2 →	+0.062	+4.082	<.001	.001	3	1
LUNG_NSCLC_LUAD	NEUROD4 →	+0.069	+3.215	<.001	.007	3	1
LUNG_NSCLC_LUAD	ASB15 →	+0.017	+3.605	.003	.007	3	1
LUNG_NSCLC_LUAD	NXNL1 →	+0.032	+4.228	<.001	<.001	3	1
LUNG_NSCLC_LUAD	OR6B2 →	+0.037	+3.857	<.001	.001	3	1
LUNG_NSCLC_LUAD	FOXB2 →	+0.831	+4.266	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

CUX2 by OR56A1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →