OR56A1

Across TCGA cell cohorts, OR56A1 mutation is significantly associated with the mutation status of many other genes, with 409 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR56A1-associated genes across cancer lineages are AASDH, ITGAE, and OR5W2. Each is linked with OR56A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR56A1-to-partner and partner-to-OR56A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AASDH grouped by OR56A1-low versus OR56A1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR56A1→partner) and Y-score (partner→OR56A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	AASDH →	+4.392	+4.392	.009	.009	1	3
LUNG_NSCLC_LUAD	ITGAE →	+3.718	+3.718	.003	.003	1	2
LUNG_NSCLC_LUAD	OR5W2 →	+3.303	+3.478	.006	.006	1	2
LUNG_NSCLC_LUAD	IPO4 →	+4.303	+4.000	.001	.001	1	2
BLOOD_Lymphoma	IKZF3 →	+4.014	+4.969	.008	.008	1	2
BREAST	PKN1 →	+4.095	+4.095	.002	.002	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 409 associations by consensus.

AASDH by OR56A1 expression — SKIN

Explore this box plot interactively →