OR52S1P

Across TCGA pan-cancer cohorts, OR52S1P RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated OR52S1P data layer.

The strongest signal is observed in pheochromocytoma and paraganglioma (PCPG), where higher OR52S1P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated OR52S1P expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

PCPG, SKCM, and THCA are the cancer types where OR52S1P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PCPG	OS	Tertile	All	0.009	0.946	<.001	36	view →
SKCM	OS	Tertile	II,III,IV	0.247	0.737	.001	27	view →
THCA	OS	Tertile	All	0.323	0.955	.005	24	view →
KIRC	DFS	Tertile	IV	0.158	0.647	.003	18	view →
HNSC	OS	Tertile	IV	1.000	0.352	.037	15	view →
UCEC	OS	Tertile	All	0.192	0.682	.026	12	view →
SARC	DFS	Tertile	All	0.095	0.632	.002	9	view →
STAD	DFS	Tertile	All	0.483	0.668	.022	9	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

OR52S1P–PCPG (OS)

Open the PCPG breakdown →