OR52R1

Across TCGA cell cohorts, OR52R1 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR52R1-associated genes across cancer lineages are CENPVL1, ASB17, and CRYBA1. Each is linked with OR52R1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52R1-to-partner and partner-to-OR52R1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CENPVL1 grouped by OR52R1-low versus OR52R1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52R1→partner) and Y-score (partner→OR52R1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CENPVL1 →	+0.127	+2.925	.001	.007	3	2
OVARY	ASB17 →	+0.023	+5.807	<.001	.001	3	1
LUNG_NSCLC_LUAD	CRYBA1 →	+0.104	+3.121	<.001	.002	3	1
LUNG_NSCLC_LUAD	ZBTB16 →	+0.184	+3.515	.003	.004	3	1
LUNG_NSCLC_LUAD	UBE2U →	+0.083	+2.786	<.001	.007	3	1
LUNG_NSCLC_LUAD	DPRX →	+0.131	+3.491	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

CENPVL1 by OR52R1 expression — LARGE_INTESTINE

Explore this box plot interactively →