Across TCGA pan-cancer cohorts, OR52P1P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of OR52P1P’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where OR52P1P RNA is repressed in tumor relative to normal tissue. In most cancer types OR52P1P is over-expressed in tumor, although a few such as LUSC and UCEC show the opposite, repressed pattern.
LUSC, KIRC, and UCEC are the cancer types where OR52P1P tumor–normal differential expression is most reproducible.