OR52N4

Across TCGA patient cohorts, OR52N4 mutation is significantly associated with the RNA expression of many other genes, with 2,296 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR52N4-associated genes across cancer lineages are PDCD2L, CTU2, and RNA5SP417. Each is linked with OR52N4 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR52N4-to-partner and partner-to-OR52N4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDCD2L grouped by OR52N4-low versus OR52N4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52N4→partner) and Y-score (partner→OR52N4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCD2L →	+0.418	+1.949	.006	.009	3	3
UCEC	CTU2 →	+0.665	+3.765	<.001	<.001	3	3
UCEC	RNA5SP417 →	+0.517	+2.236	<.001	.004	3	3
UCEC	HSPE1-MOB4 →	+0.156	+1.951	.001	.009	3	2
UCEC	CTAGE15 →	+0.161	+2.278	.009	.008	3	2
UCEC	IGLL4P →	+0.381	+1.893	.008	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,296 associations by consensus.

PDCD2L by OR52N4 expression — UCEC

Explore this box plot interactively →