OR52N4

Across TCGA patient cohorts, OR52N4 mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR52N4-associated genes across cancer lineages are ACC1, Notch1, and Rad50. Each is linked with OR52N4 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR52N4-to-partner and partner-to-OR52N4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACC1 grouped by OR52N4-low versus OR52N4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52N4→partner) and Y-score (partner→OR52N4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACC1 →	+0.366	+2.000	.025	.032	3	2
UCEC	Notch1 →	+0.137	+3.009	.030	.019	3	2
UCEC	Rad50 →	-0.287	-2.000	.008	.032	3	2
UCEC	Caspase-7-cleavedD198 →	+0.822	+2.341	.002	.019	3	2
UCEC	EGFR →	-0.155	-2.000	.031	.032	3	1
UCEC	MAPK_pT202_Y204 →	-0.509	-3.169	.016	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

ACC1 by OR52N4 expression — UCEC

Explore this box plot interactively →