OR52N4

Across TCGA cell cohorts, OR52N4 RNA expression is significantly associated with the go_rna of many other GO terms, with 766 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OR52N4-associated GO terms across cancer lineages are Endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), Interferon-mediated signaling pathway, and Activation of innate immune response. Each is linked with OR52N4 in more than 5 cancer types. Because this analysis shows association rather than direction, both OR52N4-to-partner and partner-to-OR52N4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) grouped by OR52N4-low versus OR52N4-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52N4→partner) and Y-score (partner→OR52N4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	-0.083	-0.234	.001	.008	3	6
BLOOD_Lymphoma	Interferon-mediated signaling pathway →	+0.095	+0.180	<.001	.004	3	5
BLOOD_Lymphoma	Activation of innate immune response →	+0.044	+0.189	.007	.007	2	6
BLOOD_Lymphoma	Cytoplasmic pattern recognition receptor signaling pathway →	+0.060	+0.198	.003	.006	3	5
BLOOD_Lymphoma	Innate immune response-activating signaling pathway →	+0.047	+0.189	.002	.002	3	5
BLOOD_Lymphoma	Intracellular receptor signaling pathway →	+0.039	+0.227	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 766 associations by consensus.

Endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) by OR52N4 expression — KIDNEY

Explore this box plot interactively →