OR52N4

Across TCGA cell cohorts, OR52N4 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible OR52N4-associated genes across cancer lineages are ADAM30, OR6T1, and TAS2R60. Each is linked with OR52N4 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52N4-to-partner and partner-to-OR52N4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADAM30 grouped by OR52N4-low versus OR52N4-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52N4→partner) and Y-score (partner→OR52N4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	ADAM30 →	+0.013	+4.807	<.001	.006	3	1
STOMACH	OR6T1 →	+0.084	+4.285	<.001	.007	3	1
STOMACH	TAS2R60 →	+0.174	+4.432	<.001	.003	3	1
STOMACH	OR6M1 →	+0.050	+4.285	<.001	.007	3	1
LARGE_INTESTINE	GSG1L2 →	+0.016	+4.437	<.001	.004	3	1
LUNG_NSCLC_LUAD	DEFA3 →	+0.162	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

ADAM30 by OR52N4 expression — BLOOD_Myeloma

Explore this box plot interactively →