OR52N2

Across TCGA patient cohorts, OR52N2 mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR52N2-associated genes across cancer lineages are PRDX1, A-Raf_pS299, and eEF2. Each is linked with OR52N2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52N2-to-partner and partner-to-OR52N2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRDX1 grouped by OR52N2-low versus OR52N2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52N2→partner) and Y-score (partner→OR52N2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	PRDX1 →	+0.395	+3.000	.001	.034	3	2
LUSC	A-Raf_pS299 →	+0.267	+3.009	.039	.019	3	1
UCEC	eEF2 →	+0.568	+3.584	<.001	.002	3	1
UCEC	ERK2 →	+0.440	+3.584	<.001	.002	3	1
UCEC	ETS-1 →	+0.428	+3.321	.005	.010	3	1
UCEC	JNK_pT183_Y185 →	-0.317	-3.571	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

PRDX1 by OR52N2 expression — SKCM

Explore this box plot interactively →