OR52N2

Across TCGA cell cohorts, OR52N2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR52N2-associated genes across cancer lineages are SLC15A5, MAGEB4, and NLRP8. Each is linked with OR52N2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52N2-to-partner and partner-to-OR52N2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC15A5 grouped by OR52N2-low versus OR52N2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52N2→partner) and Y-score (partner→OR52N2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SLC15A5 →	+0.023	+5.415	<.001	.004	3	1
SKIN	MAGEB4 →	+0.013	+6.022	<.001	.001	3	1
SKIN	NLRP8 →	+0.033	+4.977	<.001	.007	3	1
SKIN	KIR2DS4 →	+0.013	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

SLC15A5 by OR52N2 expression — LARGE_INTESTINE

Explore this box plot interactively →