Across TCGA patient cohorts, OR52M1 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR52M1-associated genes across cancer lineages are VEGFR2, Cyclin-B1, and p38-MAPK_pT180_Y182. Each is linked with OR52M1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52M1-to-partner and partner-to-OR52M1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52M1→partner) and Y-score (partner→OR52M1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	VEGFR2 →	+0.287	+2.128	.027	.010	3	2
UCEC	Cyclin-B1 →	+0.558	+2.115	.022	.019	3	2
SKCM	p38-MAPK_pT180_Y182 →	-0.305	-2.115	.008	.017	3	2
SKCM	YB-1 →	+0.172	+1.427	.012	.025	3	2
UCEC	ERK2 →	+0.286	+2.321	<.001	.033	3	1
UCEC	MEK1 →	+0.518	+3.906	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration

OR52M1 survival (RNA) · tumor vs normal (RNA) · all OR52M1 data types