Across TCGA patient cohorts, OR52L1 mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR52L1-associated genes across cancer lineages are IRS1, Caspase-8, and Lck. Each is linked with OR52L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52L1-to-partner and partner-to-OR52L1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52L1→partner) and Y-score (partner→OR52L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IRS1 →	+0.256	+2.115	.004	.019	3	2
UCEC	Caspase-8 →	-0.216	-2.459	.049	.019	3	2
LUAD	Lck →	+0.228	+2.195	.039	.032	3	1
LUAD	4E-BP1_pT37_T46 →	-0.575	-3.321	.002	.010	2	2
SKCM	PR →	+0.070	+3.472	.031	.002	3	1
SKCM	SLC1A5 →	-0.271	-3.169	.042	.017	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

OR52L1 survival (RNA) · tumor vs normal (RNA) · all OR52L1 data types