OR52K2

Across TCGA patient cohorts, OR52K2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,256 significant associations in total. STAD shows the largest number of these associations.

The most reproducible OR52K2-associated GO terms across cancer lineages are Positive regulation of pattern recognition receptor signaling pathway, Activation of innate immune response, and Receptor-mediated endocytosis. Each is linked with OR52K2 in more than 14 cancer types. Because this analysis shows association rather than direction, both OR52K2-to-partner and partner-to-OR52K2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of pattern recognition receptor signaling pathway grouped by OR52K2-low versus OR52K2-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52K2→partner) and Y-score (partner→OR52K2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of pattern recognition receptor signaling pathway →	+0.064	+0.041	<.001	<.001	3	15
ESCA	Activation of innate immune response →	+0.055	+0.041	<.001	<.001	3	15
ESCA	Receptor-mediated endocytosis →	+0.049	+0.042	<.001	.001	3	15
ESCA	Type I interferon production →	+0.072	+0.030	<.001	<.001	3	15
ESCA	Negative regulation of immune response →	+0.055	+0.029	<.001	<.001	3	14
ESCA	Cellular response to biotic stimulus →	+0.055	+0.024	<.001	.002	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,256 associations by consensus.

Positive regulation of pattern recognition receptor signaling pathway by OR52K2 expression — ESCA

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