OR52K2

Across TCGA patient cohorts, OR52K2 mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR52K2-associated genes across cancer lineages are Lck, SLC1A5, and TFRC. Each is linked with OR52K2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52K2-to-partner and partner-to-OR52K2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lck grouped by OR52K2-low versus OR52K2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52K2→partner) and Y-score (partner→OR52K2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Lck →	-0.371	-1.678	.003	.022	3	2
SKCM	SLC1A5 →	+0.314	+2.474	.037	.010	3	2
SKCM	TFRC →	+0.537	+3.247	.011	<.001	3	2
SKCM	CD49b →	+0.231	+2.321	.009	.033	3	2
SKCM	Di-Ras3 →	+0.128	+1.597	.018	.040	3	2
UCEC	Annexin-1 →	+0.730	+3.189	.002	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Lck by OR52K2 expression — SKCM

Explore this box plot interactively →