OR52K2

Across TCGA cell cohorts, OR52K2 mutation is significantly associated with the mutation status of many other genes, with 1,040 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OR52K2-associated genes across cancer lineages are HIF1A, H1-3, and KIF1A. Each is linked with OR52K2 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR52K2-to-partner and partner-to-OR52K2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HIF1A grouped by OR52K2-low versus OR52K2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52K2→partner) and Y-score (partner→OR52K2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	HIF1A →	+4.339	+4.339	.009	.009	1	4
BLOOD_Leukemia	H1-3 →	+5.560	+4.736	.003	.003	1	3
BLOOD_Leukemia	KIF1A →	+2.975	+3.794	.006	.006	1	3
BLOOD_Leukemia	KASH5 →	+5.560	+4.736	.003	.003	1	3
LARGE_INTESTINE	BEST2 →	+2.865	+4.217	.007	.007	1	2
LARGE_INTESTINE	EYA2 →	+2.865	+4.217	.007	.007	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,040 associations by consensus.

HIF1A by OR52K2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →