OR52I1

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR52I1 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR52I1-associated genes across cancer lineages are MSC, mv Endothelial cells, and Osteoblast. Each is linked with OR52I1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52I1-to-partner and partner-to-OR52I1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MSC grouped by OR52I1-low versus OR52I1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52I1→partner) and Y-score (partner→OR52I1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMSC →+0.242+3.169.035.02031
UCECmv Endothelial cells →-0.027-3.159.036.02031
SKCMOsteoblast →-0.046-2.993.030.03712
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

MSC by OR52I1 expression — UCEC

Box plot of MSC in OR52I1-low vs OR52I1-high samples in UCEC.

Explore this box plot interactively →

Exploration