Across TCGA patient cohorts, OR52E8 mutation is significantly associated with the RNA expression of many other genes, with 1,318 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR52E8-associated genes across cancer lineages are MTND4LP17, MIR873, and RWDD1. Each is linked with OR52E8 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR52E8-to-partner and partner-to-OR52E8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52E8→partner) and Y-score (partner→OR52E8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	MTND4LP17 →	+0.051	+3.932	<.001	.009	3	3
HNSC	MIR873 →	+0.333	+7.954	<.001	.008	3	2
SKCM	RWDD1 →	+0.426	+2.820	.003	.001	3	2
SKCM	IL9 →	+0.079	+2.523	<.001	<.001	3	2
LUAD	RNU6-468P →	+0.309	+3.864	<.001	.003	3	2
LUAD	NDUFA5P8 →	+0.088	+4.569	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,318 associations by consensus.

Exploration

OR52E8 survival (RNA) · tumor vs normal (RNA) · all OR52E8 data types