Across TCGA cell cohorts, OR52E8 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR52E8-associated genes across cancer lineages are MBD3L3, CCER1, and OPN1MW. Each is linked with OR52E8 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52E8-to-partner and partner-to-OR52E8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52E8→partner) and Y-score (partner→OR52E8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	MBD3L3 →	+0.110	+5.614	<.001	.002	3	1
PANCREAS	CCER1 →	+0.006	+5.614	<.001	.002	3	1
PANCREAS	OPN1MW →	+0.028	+5.000	<.001	.006	3	1
LUNG_NSCLC_LUAD	KCNK18 →	+0.019	+5.662	<.001	.002	3	1
BLOOD_Lymphoma	GJD2 →	+0.013	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	ETDC →	+0.483	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

OR52E8 survival (RNA) · tumor vs normal (RNA) · all OR52E8 data types