OR52E2

Across TCGA cell cohorts, OR52E2 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR52E2-associated genes across cancer lineages are TPPP2, OR11G2, and GUCA2A. Each is linked with OR52E2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52E2-to-partner and partner-to-OR52E2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TPPP2 grouped by OR52E2-low versus OR52E2-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52E2→partner) and Y-score (partner→OR52E2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	TPPP2 →	+0.056	+3.632	<.001	.003	3	1
SKIN	OR11G2 →	+0.008	+3.345	.003	.007	3	1
SKIN	GUCA2A →	+0.067	+3.688	<.001	.002	3	1
LARGE_INTESTINE	CFHR2 →	+0.038	+4.022	<.001	.006	3	1
LUNG_NSCLC_LUAD	CEACAM8 →	+0.024	+3.787	<.001	.004	3	1
LUNG_NSCLC_LUAD	PTCHD1 →	+0.390	+3.643	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

TPPP2 by OR52E2 expression — SKIN

Explore this box plot interactively →