OR52E1

RNA expression — cross-omics
Cross-omicsRNA → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR52E1 RNA expression is significantly associated with the mutation status of many other genes, with 38 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR52E1-associated genes across cancer lineages are ZEB2, ARMCX1, and F8. Each is linked with OR52E1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52E1-to-partner and partner-to-OR52E1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZEB2 grouped by OR52E1-low versus OR52E1-high in LUNG_SCLC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52E1→partner) and Y-score (partner→OR52E1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCZEB2 →+3.584+0.024.003<.00132
LUNG_SCLCARMCX1 →+5.169+0.036<.001<.00131
LUNG_SCLCF8 →+2.847+0.017.009<.00131
LUNG_SCLCSUPT5H →+3.169+0.020.005<.00131
LUNG_SCLCNOTCH4 →+2.847+0.017.009<.00131
SKINDDX39B →+4.415+0.081.007<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

ZEB2 by OR52E1 expression — LUNG_SCLC

Box plot of ZEB2 in OR52E1-low vs OR52E1-high samples in LUNG_SCLC.

Explore this box plot interactively →

Exploration