Across TCGA pan-cancer cohorts, OR52B6 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated OR52B6 data layer compared with 15 for mass-spec protein.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher OR52B6 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR52B6 expression acts as an unfavorable survival marker.

CESC, GBM, and COAD are the cancer types where OR52B6 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Median	All	0.261	0.798	.006	12	view →
GBM	DFS	Median	All	0.064	0.242	.032	3	view →
COAD	DFS	Median	All	0.135	0.557	.031	3	view →
SKCM	DFS	Median	II,III,IV	0.245	0.711	.015	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: OR52B6 tumor-vs-normal RNA expression · all OR52B6 data types