Across TCGA patient cohorts, OR52B4 mutation is significantly associated with the total protein of many other genes, with 43 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR52B4-associated genes across cancer lineages are JNK_pT183_Y185, PDCD4, and Smac. Each is linked with OR52B4 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR52B4-to-partner and partner-to-OR52B4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52B4→partner) and Y-score (partner→OR52B4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK_pT183_Y185 →	-0.168	-2.308	.047	.036	3	2
UCEC	PDCD4 →	-0.622	-2.321	.008	.035	3	2
SKCM	Smac →	+0.200	+3.334	.039	.005	3	2
SKCM	STAT3_pY705 →	-0.307	-3.087	.001	<.001	3	2
SKCM	Tuberin →	+0.258	+3.169	.027	.017	3	2
UCEC	A-Raf_pS299 →	-0.164	-3.000	.006	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

Exploration

OR52B4 survival (RNA) · tumor vs normal (RNA) · all OR52B4 data types