Across TCGA cell cohorts, OR52B4 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR52B4-associated genes across cancer lineages are DRD3, FCN2, and SIGLECL1. Each is linked with OR52B4 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52B4-to-partner and partner-to-OR52B4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52B4→partner) and Y-score (partner→OR52B4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	DRD3 →	+0.012	+4.977	<.001	.007	3	1
LARGE_INTESTINE	FCN2 →	+0.024	+5.415	.007	.004	3	1
LARGE_INTESTINE	SIGLECL1 →	+0.022	+4.977	<.001	.007	3	1
LARGE_INTESTINE	CD300H →	+0.052	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

OR52B4 survival (RNA) · tumor vs normal (RNA) · all OR52B4 data types