OR52B2

Across TCGA patient cohorts, OR52B2 mutation is significantly associated with the RNA expression of many other genes, with 452 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR52B2-associated genes across cancer lineages are ESD, CDADC1, and RNU6-686P. Each is linked with OR52B2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR52B2-to-partner and partner-to-OR52B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ESD grouped by OR52B2-low versus OR52B2-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52B2→partner) and Y-score (partner→OR52B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	ESD →	+0.409	+2.596	.001	.006	3	3
SKCM	CDADC1 →	+0.452	+3.334	.007	.005	3	3
BLCA	RNU6-686P →	+0.550	+4.973	<.001	.009	3	2
HNSC	IMP3P1 →	+0.065	+3.913	<.001	.003	3	2
BRCA	RNU6-928P →	+0.406	+4.841	<.001	.006	3	2
BRCA	PDE2A-AS1 →	+0.286	+4.797	.003	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 452 associations by consensus.

ESD by OR52B2 expression — LUSC

Explore this box plot interactively →