OR52B2

Across TCGA cell cohorts, OR52B2 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR52B2-associated genes across cancer lineages are KCND3, UTF1, and TRIM49B. Each is linked with OR52B2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52B2-to-partner and partner-to-OR52B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KCND3 grouped by OR52B2-low versus OR52B2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52B2→partner) and Y-score (partner→OR52B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	KCND3 →	+0.306	+3.519	.007	.007	3	1
LARGE_INTESTINE	UTF1 →	+0.011	+3.217	.006	.006	3	1
LARGE_INTESTINE	TRIM49B →	+0.232	+3.217	<.001	.006	3	1
LARGE_INTESTINE	OR4A47 →	+0.012	+3.700	<.001	.009	3	1
LARGE_INTESTINE	LBHD2 →	+0.092	+3.103	<.001	.004	3	1
LARGE_INTESTINE	GSC2 →	+0.110	+3.103	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

KCND3 by OR52B2 expression — LARGE_INTESTINE

Explore this box plot interactively →