Across TCGA pan-cancer cohorts, OR52B1P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of OR52B1P’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where OR52B1P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR52B1P is over-expressed in tumor.
LUSC and HNSC are the cancer types where OR52B1P tumor–normal differential expression is most reproducible.