OR52A5

Across TCGA pan-cancer cohorts, OR52A5 Mutation is linked to patient survival in 7 of 34 cancer types, making it a survival-associated OR52A5 data layer compared with 11 for mass-spec protein.

The strongest signal is observed in thymoma (THYM), where higher OR52A5 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR52A5 expression acts as an unfavorable survival marker, although some lineages such as LUSC and LUAD show a favorable association.

THYM, HNSC, and STAD are the cancer types where OR52A5 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Median	III,IV	0.103	0.944	<.001	42	view →
HNSC	OS	Median	All	0.298	0.688	.014	18	view →
STAD	OS	Median	II,III,IV	0.169	0.710	<.001	12	view →
LUSC	DFS	Median	II,III,IV	1.000	0.705	.035	6	view →
LUAD	DFS	Median	II,III,IV	1.000	0.238	.031	4	view →
LIHC	DFS	Median	All	0.096	0.526	.023	3	view →
SKCM	DFS	Median	II,III,IV	0.865	0.664	.027	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

OR52A5–THYM (OS)

Open the THYM breakdown →