OR52A5

Across TCGA patient cohorts, OR52A5 mutation is significantly associated with the RNA expression of many other genes, with 2,456 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR52A5-associated genes across cancer lineages are SNRNP25, ATP5MC1, and MTND4LP24. Each is linked with OR52A5 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR52A5-to-partner and partner-to-OR52A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNRNP25 grouped by OR52A5-low versus OR52A5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52A5→partner) and Y-score (partner→OR52A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNRNP25 →	+0.467	+2.882	.004	.001	3	3
LUSC	ATP5MC1 →	+0.518	+3.471	<.001	.002	3	3
STAD	MTND4LP24 →	+0.195	+4.462	.001	<.001	3	3
SKCM	PPP2R2D →	+0.419	+3.832	<.001	<.001	3	3
SKCM	HIGD1A →	+0.502	+2.926	.001	<.001	3	3
LGG	RNF11P2 →	+0.101	+5.327	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,456 associations by consensus.

SNRNP25 by OR52A5 expression — UCEC

Explore this box plot interactively →