OR52A5

Across TCGA cell cohorts, OR52A5 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR52A5-associated genes across cancer lineages are CFAP97D2, GPR152, and CYP4F8. Each is linked with OR52A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52A5-to-partner and partner-to-OR52A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CFAP97D2 grouped by OR52A5-low versus OR52A5-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52A5→partner) and Y-score (partner→OR52A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	CFAP97D2 →	+0.020	+4.643	<.001	.008	3	1
SKIN	GPR152 →	+0.061	+3.347	<.001	.005	3	1
SKIN	CYP4F8 →	+0.019	+3.632	<.001	.003	3	1
SKIN	P2RY10 →	+0.092	+3.263	<.001	.006	3	1
LUNG_NSCLC_LUAD	OR9G4 →	+0.049	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR5M10 →	+0.019	+5.662	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

CFAP97D2 by OR52A5 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →