OR52A1

Across TCGA patient cohorts, OR52A1 mutation is significantly associated with the RNA expression of many other genes, with 1,657 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR52A1-associated genes across cancer lineages are RRP12, ARVCF, and ZDHHC8. Each is linked with OR52A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR52A1-to-partner and partner-to-OR52A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RRP12 grouped by OR52A1-low versus OR52A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52A1→partner) and Y-score (partner→OR52A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RRP12 →	+0.460	+3.119	.001	<.001	3	3
UCEC	ARVCF →	+0.543	+2.616	.005	.005	3	3
SKCM	ZDHHC8 →	+0.395	+1.480	.001	.004	3	3
LUSC	BUD31P1 →	+0.105	+3.792	.008	.002	3	2
CESC	UBTFL5 →	+0.042	+6.569	<.001	.001	3	2
UCEC	INCENP →	+0.717	+2.616	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,657 associations by consensus.

RRP12 by OR52A1 expression — UCEC

Explore this box plot interactively →