OR52A1

Across TCGA cell cohorts, OR52A1 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR52A1-associated genes across cancer lineages are KRTAP4-6, LCE6A, and UBE2D3. Each is linked with OR52A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52A1-to-partner and partner-to-OR52A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP4-6 grouped by OR52A1-low versus OR52A1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52A1→partner) and Y-score (partner→OR52A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	KRTAP4-6 →	+0.034	+4.415	<.001	.007	3	1
SKIN	LCE6A →	+0.397	+5.022	<.001	.002	3	1
LARGE_INTESTINE	UBE2D3 →	+0.565	+3.067	.002	.009	3	1
LARGE_INTESTINE	PWWP3A →	+0.679	+3.064	.007	.009	3	1
LARGE_INTESTINE	NAA15 →	+0.850	+3.215	<.001	.009	3	1
LARGE_INTESTINE	C9orf153 →	+0.220	+3.719	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

KRTAP4-6 by OR52A1 expression — SKIN

Explore this box plot interactively →