OR51V1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR51V1 mutation is significantly associated with the RNA expression of many other genes, with 2,444 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR51V1-associated genes across cancer lineages are ANAPC15P1, PRIM1, and C4orf46. Each is linked with OR51V1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR51V1-to-partner and partner-to-OR51V1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANAPC15P1 grouped by OR51V1-low versus OR51V1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51V1→partner) and Y-score (partner→OR51V1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADANAPC15P1 →+0.632+3.289<.001.00833
UCECPRIM1 →+0.659+2.354.004.00333
UCECC4orf46 →+0.645+2.815.001.00133
SKCMCCDC43 →+0.403+1.999.005.00933
SKCMMCMBP →+0.445+2.198.006.00133
SKCMWDHD1 →+0.571+1.957<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,444 associations by consensus.

ANAPC15P1 by OR51V1 expression — COAD

Box plot of ANAPC15P1 in OR51V1-low vs OR51V1-high samples in COAD.

Explore this box plot interactively →

Exploration