OR51V1

Across TCGA patient cohorts, OR51V1 mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR51V1-associated genes across cancer lineages are PKC-b-II_pS660, Annexin-1, and Caspase-7-cleavedD198. Each is linked with OR51V1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR51V1-to-partner and partner-to-OR51V1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PKC-b-II_pS660 grouped by OR51V1-low versus OR51V1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51V1→partner) and Y-score (partner→OR51V1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PKC-b-II_pS660 →	-0.333	-3.000	.009	.036	3	2
UCEC	Annexin-1 →	+0.520	+3.189	.034	.010	3	2
UCEC	Caspase-7-cleavedD198 →	+0.732	+2.479	.008	.010	3	2
LUAD	FoxM1 →	+0.338	+3.182	.001	.009	3	1
LUAD	ACC1 →	+0.407	+2.476	.010	.009	3	1
LUAD	Nrf2 →	+0.168	+1.750	.011	.049	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

PKC-b-II_pS660 by OR51V1 expression — UCEC

Explore this box plot interactively →