OR51V1

Across TCGA cell cohorts, OR51V1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR51V1-associated genes across cancer lineages are MAGEB5, SEPTIN14, and HMGB4. Each is linked with OR51V1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR51V1-to-partner and partner-to-OR51V1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB5 grouped by OR51V1-low versus OR51V1-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51V1→partner) and Y-score (partner→OR51V1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	MAGEB5 →	+0.033	+4.643	<.001	.008	3	1
SKIN	SEPTIN14 →	+0.187	+3.920	<.001	.005	3	1
SKIN	HMGB4 →	+0.022	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

MAGEB5 by OR51V1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →