OR51T1

Across TCGA patient cohorts, OR51T1 mutation is significantly associated with the total protein of many other genes, with 59 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR51T1-associated genes across cancer lineages are 4E-BP1, MSH6, and Ku80. Each is linked with OR51T1 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR51T1-to-partner and partner-to-OR51T1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 4E-BP1 grouped by OR51T1-low versus OR51T1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51T1→partner) and Y-score (partner→OR51T1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	4E-BP1 →	+0.269	+1.847	.015	.008	3	4
SKCM	MSH6 →	+0.335	+1.847	.004	.008	3	3
UCEC	Ku80 →	+0.206	+1.713	.039	.027	3	3
SKCM	ER-alpha_pS118 →	+0.110	+2.321	.021	.033	3	2
SKCM	Paxillin →	+0.366	+1.502	.014	.028	3	2
UCEC	STAT3_pY705 →	-0.385	-2.000	<.001	.029	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 59 associations by consensus.

4E-BP1 by OR51T1 expression — SKCM

Explore this box plot interactively →