OR51S1

Across TCGA patient cohorts, OR51S1 mutation is significantly associated with the RNA expression of many other genes, with 1,893 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR51S1-associated genes across cancer lineages are DNAJC24, CELF2-DT, and TIMM44. Each is linked with OR51S1 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR51S1-to-partner and partner-to-OR51S1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNAJC24 grouped by OR51S1-low versus OR51S1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51S1→partner) and Y-score (partner→OR51S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	DNAJC24 →	+0.378	+1.880	<.001	<.001	3	4
LUSC	CELF2-DT →	+0.512	+3.625	<.001	.003	3	3
UCEC	TIMM44 →	+0.447	+3.364	<.001	.004	3	3
UCEC	ABITRAM →	+0.461	+2.447	.005	.001	3	3
UCEC	DHX30 →	+0.445	+3.601	.003	.001	3	3
UCEC	NOM1 →	+0.439	+3.470	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,893 associations by consensus.

DNAJC24 by OR51S1 expression — SKCM

Explore this box plot interactively →