OR51S1

Across TCGA cell cohorts, OR51S1 mutation is significantly associated with the mutation status of many other genes, with 1,407 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR51S1-associated genes across cancer lineages are KLHDC7A, CHERP, and AFF4. Each is linked with OR51S1 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR51S1-to-partner and partner-to-OR51S1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KLHDC7A grouped by OR51S1-low versus OR51S1-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51S1→partner) and Y-score (partner→OR51S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	KLHDC7A →	+5.502	+5.502	.003	.003	1	4
LARGE_INTESTINE	CHERP →	+2.471	+2.369	.005	.005	1	3
LARGE_INTESTINE	AFF4 →	+2.248	+2.445	.003	.003	1	3
LUNG_NSCLC_LUAD	DCC →	+4.000	+5.266	<.001	<.001	1	3
SKIN	MUCL3 →	+3.035	+3.321	.008	.008	1	3
SOFT_TISSUE	ANO6 →	+5.502	+5.502	.003	.003	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,407 associations by consensus.

KLHDC7A by OR51S1 expression — SOFT_TISSUE

Explore this box plot interactively →