OR51S1

Across TCGA cell cohorts, OR51S1 mutation is significantly associated with the drug of many other genes, with 21 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR51S1-associated genes across cancer lineages are Cytarabine, Docetaxel, and Nutlin-3a (-). Each is linked with OR51S1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR51S1-to-partner and partner-to-OR51S1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytarabine grouped by OR51S1-low versus OR51S1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51S1→partner) and Y-score (partner→OR51S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Cytarabine →	+0.805	+2.722	.022	.023	3	1
LARGE_INTESTINE	Docetaxel →	+0.580	+2.710	.028	.027	3	1
LARGE_INTESTINE	Nutlin-3a (-) →	+0.779	+2.807	.013	.037	3	1
LARGE_INTESTINE	Niraparib →	+0.332	+2.678	.031	.037	3	1
LARGE_INTESTINE	Doxorubicin →	+0.742	+2.700	.048	.030	3	1
LARGE_INTESTINE	Etoposide →	+0.740	+2.491	.043	.049	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Cytarabine by OR51S1 expression — LARGE_INTESTINE

Explore this box plot interactively →