Across TCGA patient cohorts, OR51M1 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR51M1-associated genes across cancer lineages are MEK1, p38-MAPK_pT180_Y182, and PDCD4. Each is linked with OR51M1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR51M1-to-partner and partner-to-OR51M1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51M1→partner) and Y-score (partner→OR51M1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.383	+3.169	.030	.019	3	2
UCEC	p38-MAPK_pT180_Y182 →	-0.805	-3.459	<.001	.005	3	2
UCEC	PDCD4 →	-0.742	-2.459	.001	.020	3	2
UCEC	EGFR_pY1173 →	+0.078	+3.611	.044	.001	3	1
UCEC	JNK_pT183_Y185 →	-0.196	-2.446	.015	.020	3	1
UCEC	Ku80 →	+0.325	+2.472	.004	.011	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Exploration

OR51M1 survival (RNA) · tumor vs normal (RNA) · all OR51M1 data types