OR51L1

Across TCGA patient cohorts, OR51L1 mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR51L1-associated genes across cancer lineages are Cyclin-E2, STAT3_pY705, and Ku80. Each is linked with OR51L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR51L1-to-partner and partner-to-OR51L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-E2 grouped by OR51L1-low versus OR51L1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51L1→partner) and Y-score (partner→OR51L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-E2 →	+0.187	+2.817	.034	.036	3	2
SKCM	STAT3_pY705 →	-0.259	-2.115	.007	.017	3	2
UCEC	Ku80 →	+0.285	+2.183	.021	.035	3	1
UCEC	MEK1 →	+0.466	+3.169	.015	.019	3	1
UCEC	VHL →	-1.150	-3.321	.001	.010	3	1
UCEC	CD49b →	-0.390	-2.980	.008	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Cyclin-E2 by OR51L1 expression — UCEC

Explore this box plot interactively →