Across TCGA patient cohorts, OR51I2 mutation is significantly associated with the RNA expression of many other genes, with 1,960 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR51I2-associated genes across cancer lineages are HCAR1, IGF2, and PPIP5K1. Each is linked with OR51I2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR51I2-to-partner and partner-to-OR51I2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51I2→partner) and Y-score (partner→OR51I2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HCAR1 →	-0.506	-3.448	.006	.005	3	3
SKCM	IGF2 →	-1.211	-3.420	.001	.005	3	2
SKCM	PPIP5K1 →	+0.482	+2.328	.002	.003	3	2
UCEC	DOC2B →	-1.209	-2.502	<.001	.002	3	2
UCEC	RPS29P32 →	+0.472	+2.377	<.001	.002	3	2
SKCM	IGFL1P1 →	+0.727	+2.683	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,960 associations by consensus.

Exploration

OR51I2 survival (RNA) · tumor vs normal (RNA) · all OR51I2 data types