OR51I2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR51I2 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR51I2-associated genes across cancer lineages are MAGEB5, DMRTC2, and GML. Each is linked with OR51I2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR51I2-to-partner and partner-to-OR51I2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51I2→partner) and Y-score (partner→OR51I2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUSCMAGEB5 →+0.033+4.643<.001.00831
OESOPHAGUSDMRTC2 →+0.006+4.906<.001.00631
BLOOD_LeukemiaGML →+0.086+4.152<.001.00931
BLOOD_LeukemiaADAM2 →+0.113+4.539<.001.00731
BLOOD_LeukemiaIZUMO3 →+0.054+4.969<.001.00331
LARGE_INTESTINEOR10R2 →+0.031+4.977<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration