OR51G1

Across TCGA cell cohorts, OR51G1 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible OR51G1-associated genes across cancer lineages are HIGD1C, ZSCAN1, and TBL1Y. Each is linked with OR51G1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR51G1-to-partner and partner-to-OR51G1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HIGD1C grouped by OR51G1-low versus OR51G1-high in UPPER_AERODIGESTIVE_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51G1→partner) and Y-score (partner→OR51G1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	HIGD1C →	+0.074	+4.736	<.001	.009	3	2
PANCREAS	ZSCAN1 →	+0.039	+5.000	<.001	.006	3	1
PANCREAS	TBL1Y →	+0.006	+5.614	<.001	.002	3	1
SKIN	NEU2 →	+0.018	+4.977	<.001	.007	3	1
SKIN	ACTL9 →	+0.033	+6.022	<.001	.001	3	1
SKIN	IFNA4 →	+0.042	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

HIGD1C by OR51G1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →