OR51F2

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, OR51F2 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated OR51F2 data layer compared with 18 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher OR51F2 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated OR51F2 expression acts as an unfavorable survival marker, although some lineages such as UCEC and SKCM show a favorable association.

ACC, SCLC, and LUSC are the cancer types where OR51F2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ACCDFSMedianAll0.0460.753<.00136view →
SCLCOSMedianAll0.1920.720<.00136view →
LUSCOSMedianIII,IV0.0950.691<.00136view →
UCECDFSMedianAll1.0000.626.01230view →
LIHCDFSMedianAll0.0440.553<.00112view →
SKCMDFSMedianIII,IV0.7760.570.0481view →
Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

OR51F2–ACC (DFS)

Kaplan–Meier survival curve for OR51F2 mutant vs wild-type samples in ACC.

Open the ACC breakdown →

Exploration