OR51F2

Across TCGA patient cohorts, OR51F2 mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR51F2-associated genes across cancer lineages are STAT3_pY705, 4E-BP1, and Cyclin-B1. Each is linked with OR51F2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR51F2-to-partner and partner-to-OR51F2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, STAT3_pY705 grouped by OR51F2-low versus OR51F2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51F2→partner) and Y-score (partner→OR51F2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	STAT3_pY705 →	-0.517	-3.584	<.001	.002	3	2
UCEC	4E-BP1 →	+0.394	+2.199	.002	.033	3	2
UCEC	Cyclin-B1 →	+0.988	+3.169	<.001	.018	3	2
UCEC	14-3-3_beta →	-0.112	-2.301	.021	.034	3	1
UCEC	FoxM1 →	+0.266	+2.459	.033	.020	3	1
UCEC	Heregulin →	-0.123	-3.000	.038	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

STAT3_pY705 by OR51F2 expression — UCEC

Explore this box plot interactively →